1. Harmine inhibits phophodiesterase and increases cAMP & cGMP levels, thus reduce the level of free radicals,
2. Harmine depresses the amplitude of the action potential and the maximum velocity of the upstroke,
3. Harmine possesses cytotoxic and genotoxic activity, helpful to cure tumor cells,
4. Harmine is a potent antinociceptive agent,
5. Harmine shows significant vasorelaxant effect.